Penicillin G potassium
USP/1502508 - United States Pharmacopeia (USP) Reference Standard
Synonym: Penicillin G potassium salt; Benzylpenicillin potassium salt
CAS Number: 113-98-4
Empirical Formula (Hill Notation): C16H17KN2O4S
Molecular Weight: 372.48
MDL Number: MFCD00036193
Linear Formula: C16H17KN2O4S
Product Type: Chemical
| API family | penicillin & derivatives |
| application(s) | USP Biologics pharmaceutical (small molecule) |
| form | powder |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C16H18N2O4S.K/c1-16(2) |
| InChI key | IYNDLOXRXUOGIU-LQDWTQKMSA |
| manufacturer/tradename | USP |
| SMILES string | [K+].[H][C@]12SC(C)(C)[C@ |
| Application: | Penicillin G potassium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as: • Penicillamine • Penicillin G Benzathine • Penicillin G Benzathine and Penicillin G Procaine Injectable Suspension • Penicillin G Benzathine Injectable Suspension • Penicillin G Potassium • Penicillin G Potassium for Injection • Penicillin G Potassium for Oral Solution |
| Biochem/physiol Actions: | Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking. Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria. |
| General description: | Penicillin G potassium is a natural β-lactam antibiotic that targets bacterial cell wall synthesis by inhibiting transpeptidase enzymes. It is effective against non-β-lactamase-producing Gram-positive organisms. The USP standard facilitates microbiological potency tests and purity analysis. The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle. The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics. |
| Other Notes: | Sales restrictions may apply. |
| Other Notes: | This product is part of the USP Biologics program. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H317 |
| Precautionary statements | P280 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 41116107 |