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Olopatadine hydrochloride

USP/1478403 - United States Pharmacopeia (USP) Reference Standard

Synonym: (11Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride; AL-4943A; KW-4679; Opatanol; Patanol

CAS Number: 140462-76-6
Empirical Formula (Hill Notation): C21H23NO3·HCl
Molecular Weight: 373.87
MDL Number: MFCD00875716
Linear Formula: C21H23NO3·HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-1478403-150MG 150 mg
 $556.00
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API family olopatadine
application(s) pharmaceutical (small molecule)
format neat
grade pharmaceutical primary standard
InChI 1S/C21H23NO3.ClH/c1-22(2)11-5-8-18-17-7-4-3-6-16(17)14-25-20-10-9-15(12-19(18)20)13-21(23)24;/h3-4,6-10,12H,5,11,13-14H2,1-2H3,(H,23,24);1H/b18-8-;
InChI key HVRLZEKDTUEKQH-NOILCQHBSA-N
manufacturer/tradename USP
SMILES string Cl.CN(C)CCC=C1c2ccccc2COc3ccc(CC(O)=O)cc13
Analysis Note: These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
Application: Olopatadine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
•  Olopatadine Hydrochloride Ophthalmic Solution
Biochem/physiol Actions: Olopatadine is a dual acting histamine H1-receptor antagonist and mast cell stabilizer.
Biochem/physiol Actions: Olopatadine is a histamine H1 receptor antagonist and mast cell stabilizer. The low level of occupancy H1 receptors in the brain explains the low sedation effect of olopatidine. It is believed that olopatidine is a substrate for P-glycoprotein, which limits its brain penetration.
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes: Sales restrictions may apply.
UNSPSC 41116107

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