Dexamethasone acetate
USP/1176506 - United States Pharmacopeia (USP) Reference Standard
Synonym: Dexamethasone 21-acetate; 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate; 9α-Fluoro-16α-methylprednisolone-21-acetate; Prednisolone F acetate
CAS Number: 1177-87-3
Empirical Formula (Hill Notation): C24H31FO6
Molecular Weight: 434.50
MDL Number: MFCD00027407
Linear Formula: C24H31FO6
Product Type: Chemical
| agency | USP |
| API family | dexamethasone |
| application(s) | pharmaceutical (small molecule) |
| biological source | synthetic |
| color | white |
| form | powder |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C24H31FO6/c1-13-9-18-1 |
| InChI key | AKUJBENLRBOFTD-RPRRAYFGSA |
| manufacturer/tradename | USP |
| mp | 460.4-464 °F (238—240°C) |
| packaging | pkg of 200 mg |
| SMILES string | [H][C@@]12CCC3=CC(=O)C=C[ |
| solubility | acetone: freely soluble |
| dichloromethane: slightly soluble | |
| methanol: freely soluble | |
| water: practically insoluble | |
| storage temp. | 2-8°C |
| vapor pressure | <0.0000001 kPa ( 25 °C) |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Dexamethasone acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as: • Betamethasone Acetate • Ciprofloxacin and Dexamethasone Otic Suspension • Dexamethasone • Dexamethasone Acetate • Dexamethasone Acetate Injectable Suspension |
| General description: | Dexamethasone acetate (Decadron-LA) belongs to the class of long-acting glucocorticoids, commonly used as a pharmaceutical ingredient in creams, ointments, microemulsions, lotions, aerosols, etc. This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia ![]() |
| Other Notes: | Sales restrictions may apply. |
| Symbol | GHS08 |
| Signal word | Danger |
| Hazard statements | H360FD |
| Precautionary statements | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 460.4-464 °F (238—240°C) |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |


