Butylated hydroxytoluene
USP/1082708 - United States Pharmacopeia (USP) Reference Standard
Synonym: 2,6-Di-tert-butyl-4-methylphenol; 2,6-Di-tert-butyl-p-cresol; BHT; Butylated hydroxytoluene; Butylhydroxytoluene; DBPC
CAS Number: 128-37-0
Empirical Formula (Hill Notation): C15H24O
Molecular Weight: 220.35
EC Number: 204-881-4
MDL Number: MFCD00011644
Linear Formula: [(CH3)3C]2C6H2(CH3)OH
Product Type: Chemical
| API family | butylated hydroxytoluene |
| application(s) | USP Biologics pharmaceutical (small molecule) |
| autoignition temp. | 878 °F |
| bp | 265 °C (lit.) |
| form | crystalline powder |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C15H24O/c1-10-8-11(14( |
| InChI key | NLZUEZXRPGMBCV-UHFFFAOYSA |
| manufacturer/tradename | USP |
| mp | 69-73 °C (lit.) |
| SMILES string | Cc1cc(c(O)c(c1)C(C)(C)C)C |
| vapor density | 7.6 (vs air) |
| vapor pressure | <0.01 mmHg ( 20 °C) |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Butylated hydroxytoluene USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as: • Dutasteride and Tamsulosin Hydrochloride Capsules |
| General description: | Butylated hydroxytoluene (BHT) is a synthetic antioxidant commonly used in biologic formulations to prevent oxidative degradation. It acts as a preservative, protecting biologic products from oxidation, which can affect the potency and stability of sensitive molecules. Its application is critical in maintaining the integrity of biologics, particularly those that are exposed to air or light during production and storage. The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics. |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Other Notes: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia . |
| Other Notes: | Sales restrictions may apply. |
| Other Notes: | This product is part of USP Biologics Program. |
| Other Notes: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Ph |
| Symbol |  GHS09 |
| Signal word | Warning |
| Hazard statements | H410 |
| Precautionary statements | P273 |
| Hazard Codes | N |
| Risk Statements | 50/53 |
| Safety Statements | 60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 2 |
| Flash Point(F) | 260.6 °F - open cup |
| Flash Point(C) | 127 °C - open cup |
| bp | 265 °C (lit.) |
| mp | 69-73 °C (lit.) |
| UNSPSC | 41116107 |