4-Aminophenol
USP/1021204 - United States Pharmacopeia (USP) Reference Standard
Synonym: 4-Hydroxyaniline
CAS Number: 123-30-8
Empirical Formula (Hill Notation): C6H7NO
Molecular Weight: 109.13
MDL Number: MFCD00007869
Linear Formula: H2NC6H4OH
Product Type: Chemical
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C6H7NO/c7-5-1-3-6(8)4- |
| InChI key | PLIKAWJENQZMHA-UHFFFAOYSA |
| manufacturer/tradename | USP |
| mp | 185-189 °C (lit.) |
| SMILES string | Nc1ccc(O)cc1 |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | This USP reference standard is intended for use in specified quality tests and assays. Also used to prepare standard and system suitability solutions to test for the presence of 4-aminophenol as an impurity in various pharmaceutical dosage forms of acetaminophen, according to the United States Pharmacopeia (USP) monographs:• Mesalamine • Acetaminophen Tablets • Acetaminophen Oral Suspension • Tramadol Hydrochloride and Acetaminophen Tablets |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia   .4-Aminophenol is the principal degradation product of acetaminophen, formed as an impurity during its hydrolysis. |
| Other Notes: | Sales restrictions may apply. |
| Other Notes: | USP issued SDS can be found here . |
| Symbol |    GHS07,GHS08,GHS09 |
| Signal word | Warning |
| Hazard statements | H302 + H332 - H317 - H341 - H373 - H410 |
| Precautionary statements | P273 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P308 + P313 |
| RIDADR | UN 2512 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 185-189 °C (lit.) |
| UNSPSC | 41116107 |