Sorafenib tosilate
SUPELCO/Y0002224 - CRS, European Pharmacopoeia (EP) Reference Standard
Synonym: Sorafenib tosylate; 4-
CAS Number: 475207-59-1
Empirical Formula (Hill Notation): C21H16ClF3N4O3·C7H8SO3
Molecular Weight: 637.03
MDL Number: MFCD08235032
Linear Formula: C21H16ClF3N4O3·C7H8SO3
Product Type: Chemical
InChI | 1S/C21H16ClF3N4O3.C7H8O3S |
InChI key | IVDHYUQIDRJSTI-UHFFFAOYSA |
manufacturer/tradename | EDQM |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Tosylate salt of the orally active kinase inhibitor Sorafenib (BAY 43-9006) that exerts broad-spectrum anticancer efficacy in vitro and in vivo via targeting b-Raf, c-Raf (Raf-1), as well as several receptor tyrosine kinases involved in neovascularization and tumor progression, including vascular endothelial growth factor receptors 2/3 (VEGFR-2/Flk-1/KDR, VEGFR-3), platelet-derived growth factor receptor-beta (PDGFR-β), Flt-3, c-KIT, FGFR-1 (Flt-2) and RET. |
General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia . |
Other Notes: | Sales restrictions may apply. |
Packaging: | Unit quantity: 120 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue . |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |