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Favipiravir

SUPELCO/PHR9070 - certified reference material, TraceCERT®

Synonym: 6-Fluoro-3-hydroxy-2-pyrazinecarboxamide; 6-fluoro-3,4-dihydro-3-oxo-2-pyrazinecarboxamide; Avigan; T-705; T705

CAS Number: 259793-96-9
Empirical Formula (Hill Notation): C5H4FN3O2
Molecular Weight: 157.10
MDL Number: MFCD12032148
Linear Formula: C5H4FN3O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-PHR9070-50MG 50 mg
 No Price  

 

form solid
grade TraceCERT®
  certified reference material
product line TraceCERT®
Quality Level 300 
shelf life limited shelf life, expiry date on the label
SMILES string FC1=CNC(C(C(N)=O)=N1)=O
storage temp. −20°C
Biochem/physiol Actions: Favipiravir (T-705) is an inhibitor of viral RNA polymerase. In cells, the comound is converted to T-705-4-ribofuranosyl-5-triphosphate, which selectively targets the viral polymerase without affecting mammalian RNA or DNA polymerases. Favipiravir inhibits replication of inluenza viruse A, B and C with IC50 values between 0.013 and 0.48 mM. The compound protects mice from lethal-dose infections of wild type and neuraminidase inhibitor-resistant strains of H5N1 viruses, Favipiravir has been found to have activity against many viruses including flavi-, alpha-, filo-, bunya-, arena-, noro-, and of other RNA viruses, and is already used off-label for Ebola and Lassa virus.
General description: This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com
Legal Information: TraceCERT is a registered trademark of Sigma-Aldrich Co. LLC
Storage Temp. −20°C
UNSPSC 41116107

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