Synonym: 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one; 7-Methoxy-5,11,12-trihydroxycoumestan
CAS Number: 524-12-9
Empirical Formula (Hill Notation): C16H10O7
Molecular Weight: 314.25
MDL Number: MFCD07778564
Linear Formula: C16H10O7
Product Type: Chemical
assay |
≥90.0% (HPLC) |
form |
solid |
grade |
primary reference standard |
InChI |
1S/C16H10O7/c1-21-6-2-10(19)14-12(3-6)23-16(20)13-7-4-8(17)9(18)5-11(7)22-15(13)14/h2-5,17-19H,1H3 |
InChI key |
XQDCKJKKMFWXGB-UHFFFAOYSA-N |
manufacturer/tradename |
PhytoLab |
product line |
phyproof® Reference Substance |
SMILES string |
COc1cc(O)c-2c(OC(=O)c3c-2oc4cc(O)c(O)cc34)c1 |
storage temp. |
2-8°C |
Biochem/physiol Actions: |
Wedelolactone inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα. Irreversible inhibitor of IKKα and β kinase activity (IC50 < 10 μM). Wedelolactone has no effects on p38 MAP kinase or Akt. |
General description: |
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG |
Legal Information: |
phyproof is a registered trademark of PhytoLab GmbH & Co. KG |
Purity |
≥90.0% (HPLC) |
Storage Temp. |
2-8°C |
UNSPSC |
41116107 |