Synonym: 4′,5,6,7-Tetrahydroxyflavone 7-glucuronide; 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid; 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Breviscapin; Scutellarein-7-O-β-D-glucuronide
CAS Number: 27740-01-8
Empirical Formula (Hill Notation): C21H18O12
Molecular Weight: 462.36
MDL Number: MFCD01861503
Linear Formula: C21H18O12
Product Type: Chemical
assay |
≥95.0% (HPLC) |
form |
solid |
grade |
primary reference standard |
InChI |
1S/C21H18O12/c22-8-3-1-7(2-4-8)10-5-9(23)13-11(31-10)6-12(14(24)15(13)25)32-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-22,24-28H,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1 |
InChI key |
DJSISFGPUUYILV-ZFORQUDYSA-N |
manufacturer/tradename |
PhytoLab |
product line |
phyproof® Reference Substance |
SMILES string |
O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2cc3OC(=CC(=O)c3c(O)c2O)c4ccc(O)cc4 |
Biochem/physiol Actions: |
Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS. |
General description: |
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG |
Legal Information: |
phyproof is a registered trademark of PhytoLab GmbH & Co. KG |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥95.0% (HPLC) |
UNSPSC |
41116107 |