Osthole
SUPELCO/PHL89747 - phyproof® Reference Substance
Synonym: 7-
CAS Number: 484-12-8
Empirical Formula (Hill Notation): C15H16O3
Molecular Weight: 244.29
MDL Number: MFCD00076049
Linear Formula: C15H16O3
Product Type: Chemical
assay | ≥95.0% (HPLC) |
form | solid |
grade | primary reference standard |
InChI | 1S/C15H16O3/c1-10(2)4-7-1 |
InChI key | MBRLOUHOWLUMFF-UHFFFAOYSA |
manufacturer/tradename | PhytoLab |
product line | phyproof® Reference Substance |
SMILES string | COc1ccc2C=CC(=O)Oc2c1CC= |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Active constituent of Cnidium monnieri, a traditional Chinese medicine used for its anti-inflammatory, analgesic, and anti-lipedemic activities. Dramatically decreased lipid accumulation in a quail model. Its neuroprotective effect on MPP(+)-induced cytotoxicity in PC12 cells supports the use of osthole as a therapeutic agent for the treatment of neurodegenerative disorders. Suppression of fatty acid synthase expression in HER2-overexpressing breast cancer cells indicates osthole as a promising agent for chemotherapy. |
General description: | This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG. |
Legal Information: | phyproof is a registered trademark of PhytoLab GmbH & Co. KG |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95.0% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |