Synonym: (Z)-Guggulsterone; (17Z)-Pregna-4,17(20)-diene-3,16-dione; 4,17(20)-trans-Pregnadiene-3,16-dione
CAS Number: 39025-23-5
Empirical Formula (Hill Notation): C21H28O2
Molecular Weight: 312.45
MDL Number: MFCD01310757
Linear Formula: C21H28O2
Product Type: Chemical
assay |
≥90.0% (HPLC) |
form |
solid |
grade |
primary reference standard |
InChI |
1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1 |
InChI key |
WDXRGPWQVHZTQJ-OSJVMJFVSA-N |
manufacturer/tradename |
PhytoLab |
product line |
phyproof® Reference Substance |
SMILES string |
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)C(=CC)C(=O)C[C@@]24[H] |
Biochem/physiol Actions: |
(Z)-Guggulsterone is a natural product that lowers cholesterol due to its function as an antagonist ligand for the bile acid receptor. (Z)-Guggulsterone is a nuclear hormone receptor that regulates the transcription of several genes involved in cholesterol metabolism and plays a role in cholesterol level regulation. (Z)-Guggulsterone is also a selective farnesoid X receptor (FXR) modulator. |
General description: |
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG |
Legal Information: |
phyproof is a registered trademark of PhytoLab GmbH & Co. KG |
Symbol |
GHS07 |
Signal word |
Warning |
Hazard statements |
H335 |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥90.0% (HPLC) |
UNSPSC |
41116107 |