Synonym: 4′,5,7-Trihydroxyflavone; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone
CAS Number: 520-36-5
Empirical Formula (Hill Notation): C15H10O5
Molecular Weight: 270.24
MDL Number: MFCD00006831
Linear Formula: C15H10O5
Product Type: Chemical
assay |
≥95.0% (HPLC) |
form |
powder |
grade |
primary reference standard |
InChI |
1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H |
InChI key |
KZNIFHPLKGYRTM-UHFFFAOYSA-N |
manufacturer/tradename |
PhytoLab |
mp |
>300 °C (lit.) |
product line |
phyproof® Reference Substance |
SMILES string |
Oc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)cc3O2 |
Biochem/physiol Actions: |
A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53. Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication. |
General description: |
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG |
Legal Information: |
phyproof is a registered trademark of PhytoLab GmbH & Co. KG |
Purity |
≥95.0% (HPLC) |
mp |
>300 °C (lit.) |
UNSPSC |
41116107 |