Urocortin III human
SIGMA/U1008 - ≥97% (HPLC)
CAS Number: 351999-19-4
Empirical Formula (Hill Notation): C185H307N53O50S2
Molecular Weight: 4137.87
MDL Number: MFCD03792654
Linear Formula: C185H307N53O50S2
Product Type: Chemical
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| assay | ≥97% (HPLC) |
| biological source | human |
| form | solid |
| Quality Level | 200  |
| storage temp. | −20°C |
| technique(s) | ligand binding assay: suitable |
| UniProt accession no. | Q969E3  |
| Amino Acid Sequence: | Phe-Thr-Leu-Ser-Leu-Asp-V |
| Application: | Urocortin III human can be used as a test compound for studying the impacts of melanocortin agonist on in vitro α-subunit secretion. |
| Biochem/physiol Actions: | Selective ligand with high affinity for CRF2 Receptors |
| Biochem/physiol Actions: | Urocortin III belongs to corticotropin-releasing hormone family with high affinity for the type 2 corticotropin-releasing factor (CRFR2) receptor. It stimulates insulin and glucagon secretion.Urocortin III also possesses cardioprotective property and has minimal impact on the hypothalamic stress axis. It is, therefore, utilized for treating ischemic heart disease. |
| Other Notes: | Lyophilized from 0.1% TFA in H2O |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |