Trizma® hydrochloride
SIGMA/T6666 - pH 3.5-5.0 (0.5 M in H2O), BioXtra, ≥99.0% (titration)
Synonym: TRIS HCl; TRIS hydrochloride; Tris(hydroxymethyl)
CAS Number: 1185-53-1
Empirical Formula (Hill Notation): C4H11NO3 · HCl
Molecular Weight: 157.60
EC Number: 214-684-5
MDL Number: MFCD00012590
Linear Formula: NH2C(CH2OH)3 · HCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: T6666-50G
This image depicts SKU: T6666-50G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: T6666-250G
This image depicts SKU: T6666-250G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: T6666-1KG
This image depicts SKU: T6666-1KG
| absorption | ≤0.010 at 280 in H2O at 0.5 M |
| ≤0.015 at 260 in H2O at 0.5 M | |
| anion traces | sulfate (SO42-): ≤0.005% |
| application(s) | diagnostic assay manufacturing |
| assay | ≥99.0% (titration) |
| cation traces | Al: ≤0.0005% |
| As: ≤0.0001% | |
| Ba: ≤0.0005% | |
| Bi: ≤0.0005% | |
| Ca: ≤0.001% | |
| Cd: ≤0.0005% | |
| Co: ≤0.0005% | |
| Cr: ≤0.0005% | |
| Cu: ≤0.0005% | |
| Fe: ≤0.0005% | |
| K: ≤0.005% | |
| Li: ≤0.0005% | |
| Mg: ≤0.0005% | |
| Mn: ≤0.0005% | |
| Mo: ≤0.0005% | |
| Na: ≤0.005% | |
| Ni: ≤0.0005% | |
| Pb: ≤0.0005% | |
| Sr: ≤0.0005% | |
| Zn: ≤0.0005% | |
| form | powder |
| ign. residue (900°C) | ≤0.2% (as SO4) |
| impurities | Insoluble matter, passes filter test |
| InChI | 1S/C4H11NO3.ClH/c5-4(1-6, |
| InChI key | QKNYBSVHEMOAJP-UHFFFAOYSA |
| loss | ≤0.2% loss on drying, 110°C |
| mp | 150-152 °C |
| pH | 3.5-5.0 (0.5 M in H2O) |
| pKa (25 °C) | 8.1 |
| product line | BioXtra |
| Quality Level | 400  |
| SMILES string | Cl.NC(CO)(CO)CO |
| solubility | H2O: 0.5 M, clear, colorless |
| useful pH range | 7.0-9.0 |
| Legal Information: | Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Other Notes: | Easily compare specifications for Trizma HCl products with the Trizma HCl specification table . |
| Other Notes: | The pH values of all buffers are temperature and concentration dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution. For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode. |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 50, 250 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99.0% (titration) |
| mp | 150-152 °C |
| UNSPSC | 12352104 |