Advanced Search



APRIL, Soluble mouse

SIGMA/SRP8043 - recombinant, expressed in HEK 293 cells, FLAG® tagged, >95% (SDS-PAGE)

Synonym: ACRP30headless:A-proliferation-inducing ligand; ACRP30headless:APRIL; ACRP30headless:CD256; TNFSF10

Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SRP8043-10UG 10 µg
 $477.00
1/EA		 Add To Favorites
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay >95% (SDS-PAGE)
biological source mouse
color white
form lyophilized
impurities <0.02 EU/μg endotoxin, tested
mol wt ~34 kDa by SDS-PAGE
packaging pkg of 10 μg
recombinant expressed in HEK 293 cells
shipped in wet ice
storage condition avoid repeated freeze/thaw cycles
storage temp. −20°C
tag FLAG® tagged
UniProt accession no. Q9D777 
General description: APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth, is involved in monocyte/macrophage-mediated immunological processes and functions as an important survival factor for plasmablasts and bone marrow plasma cells. APRIL is a high activity construct in which two trimeric APRIL ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively stimulates proliferation B cell. A basic amino acid sequence (QKQKKQ) close to the N-terminus of APRIL is required for binding to negatively charged sulfated glycosaminoglycan side chains of proteoglycans. Proteoglycans mediate binding of APRIL to tumor cells as well as primary lymphoid cells.
Legal Information: FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes: The extracellular domain of mouse APRIL (aa 88-232) is fused at the N-terminus to mouse ACRP30headless (aa 18-110) and a FLAG®-tag.
Physical form: Lyophilized from PBS.
Preparation Note: Reconstitute with 100 μL deionized water.
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity >95% (SDS-PAGE)
Storage Temp. −20°C
UNSPSC 12352200

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Tariffs & Effects on Pricing

Tariff note: As we navigate the current environment of tariff surcharges and mid-year manufacturer price increases, we want to keep you informed. While we have avoided making specific decisions thus far, we anticipate that we will be forced to implement a cost adjustment policy to offset the fees we have already been absorbing. We are committed to transparency and moderation in this process.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top