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Sitamaquine tosylate

SIGMA/SML1542 - ≥98% (HPLC)

Synonym: 6-Methoxy-8-(6-diethylaminohexylamine)-4-methylquinoline tosylate; N-[6-(Diethylamino)hexyl]-6-methoxy-4-methylquinolin-8-amine tosylate; N1,N1-Diethyl-N6-(6-methoxy-4-methyl-8-quinolinyl)-1,6-hexanediamine tosylate; NSC 2452; WR-6026

CAS Number: 1019640-33-5
Empirical Formula (Hill Notation): C21H33N3O · C7H8O3S
Molecular Weight: 515.71
MDL Number: MFCD17392572
Linear Formula: C21H33N3O · C7H8O3S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1542-5MG 5 mg
 $131.00
1/EA		 Add To Favorites
45-SML1542-25MG 25 mg
 $410.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML1542-25MG.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C21H33N3O.C7H8O3S/c1-5-24(6-2)14-10-8-7-9-12-22-20-16-18(25-4)15-19-17(3)11-13-23-21(19)20;1-6-2-4-7(5-3-6)11(8,9)10/h11,13,15-16,22H,5-10,12,14H2,1-4H3;2-5H,1H3,(H,8,9,10)
InChI key LOBPWLFCZDGYKW-UHFFFAOYSA-N
Quality Level 100 
SMILES string CC1=C(C=C(OC)C=C2NCCCCCCN(CC)CC)C2=NC=C1.CC3=CC=C(S(=O)(O)=O)C=C3
solubility H2O: 15 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: Sitamaquine is also known as WR-6026. It is used in the treatment of visceral leishmaniasis.
Biochem/physiol Actions: Sitamaquine is an orally active 8-aminoquinoline analog that exhibit antiplasmodial and antileishmanial activities.
Biochem/physiol Actions: Sitamaquine is an orally active 8-aminoquinoline analog that exhibit antiplasmodial and antileishmanial activities. Sitamaquine accumulates in Leishmania parasites. Sitamaquine potently inhibits respiratory chain complex II (succinate dehydrogenase), which leads to an apoptosis-like death of Leishmania parasites.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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