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FDI-6

SIGMA/SML1392 - ≥98% (HPLC)

Synonym: 3-Amino-N-(4-fluorophenyl)-6-(2-thienyl)-4-(trifluoromethyl)-thieno[2,3-b]pyridine-2-carboxamide; 3-Amino-N-(4-fluorophenyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide; NCGC00099374

CAS Number: 313380-27-7
Empirical Formula (Hill Notation): C19H11F4N3OS2
Molecular Weight: 437.43
MDL Number: MFCD01416826
Linear Formula: C19H11F4N3OS2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1392-5MG 5 mg
 $129.00
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45-SML1392-25MG 25 mg
 $509.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML1392-5MG.

 

assay ≥98% (HPLC)
color white to beige
form powder (flocculent)
InChI 1S/C19H11F4N3OS2/c20-9-3-5-10(6-4-9)25-17(27)16-15(24)14-11(19(21,22)23)8-12(26-18(14)29-16)13-2-1-7-28-13/h1-8H,24H2,(H,25,27)
InChI key ZATJMMZPGVDUOM-UHFFFAOYSA-N
Quality Level 100 
SMILES string NC1=C(C(NC2=CC=C(F)C=C2)=O)SC3=C1C(C(F)(F)F)=CC(C4=CC=CS4)=N3
solubility DMSO: 10 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: FDI-6 is a potent and specific inhibitor of FOXM1 that blocks DNA binding. FDI-6 binds to FOXM1 protein and specifically downregulates FOXM1-activated genes.
Biochem/physiol Actions: FDI-6 is a potent and specific inhibitor of FOXM1.
Biochem/physiol Actions: Forkhead domain inhibitor-6 (FDI-6) is used to treat anaemia patients because of diminished red blood production. In Hep-2 cells, FDI-6 can stimulate cell death and also helps to prevent cell proliferation, invasion and migration.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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