R-7050
SIGMA/SML1377 - ≥95% (HPLC)
Synonym: 8-
CAS Number: 303997-35-5
Empirical Formula (Hill Notation): C16H8ClF3N4S
Molecular Weight: 380.77
MDL Number: MFCD00140737
Linear Formula: C16H8ClF3N4S
Product Type: Chemical
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML1377-5MG.
This image depicts SML1377-5MG.
| assay | ≥95% (HPLC) |
| color | white to beige |
| form | powder |
| InChI | 1S/C16H8ClF3N4S/c17-9-6-7 |
| InChI key | SUUMKHOVGVYGOP-UHFFFAOYSA |
| Quality Level | 100  |
| shipped in | wet ice |
| SMILES string | ClC1=CC=C(N=C(SC2=CC=CC=C |
| solubility | DMSO: 2 mg/mL, clear (warmed) |
| storage temp. | −20°C |
| Biochem/physiol Actions: | R-7050 is a cell-permeable TNF-α receptor antagonist that blocks TNF-α-induced binding of TNF-αRI with TNFαR-associated death domain protein and receptor interacting protein 1, blocking internalization of the TNFα-TNFαR complex. R-7050 was found to reduce neurovascular injury in a mouse model of hemorrhagic stroke. |
| Biochem/physiol Actions: | R-7050 is a cell-permeable TNF-α receptor antagonist. |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 51111800 |