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Cariporide

SIGMA/SML1360 - ≥98% (HPLC)

Synonym: HOE-642; N-(Aminoiminomethyl)-4-(1-methylethyl)-3-(methylsulfonyl)-benzamide; N-(Diaminomethylene)-4-isopropyl-3-(methylsulfonyl)benzamide

CAS Number: 159138-80-4
Empirical Formula (Hill Notation): C12H17N3O3S
Molecular Weight: 283.35
Linear Formula: C12H17N3O3S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1360-5MG 5 mg
 $92.30
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45-SML1360-25MG 25 mg
 $352.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C12H17N3O3S/c1-7(2)9-5-4-8(11(16)15-12(13)14)6-10(9)19(3,17)18/h4-7H,1-3H3,(H4,13,14,15,16)
InChI key IWXNYAIICFKCTM-UHFFFAOYSA-N
Quality Level 100 
SMILES string NC(NC(C1=CC(S(C)(=O)=O)=C(C(C)C)C=C1)=O)=N
solubility DMSO: 20 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: Cariporide is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1), also known as the Na+/H+ antiporter. Cariporide has shown cardioprotective and antiarrhythmic effects, and has recently been investigated for anticancer activity.
Biochem/physiol Actions: Cariporide is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1).
Biochem/physiol Actions: Cariporide, a sodium-hydrogen exchange inhibitor can decrease the liberation of myoglobin at the time of ischemia/reperfusion and reduces the liberation of NE (norepinephrine) during ischemia.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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