4BP-TQS

SIGMA/SML1167 - ≥98% (HPLC)

Synonym: 4-(4-Bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide

CAS Number: 360791-49-7
Empirical Formula (Hill Notation): C₁₈H₁₇BrN₂O₂S
Molecular Weight: 405.31
MDL Number: MFCD00981752
Linear Formula: C₁₈H₁₇BrN₂O₂S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1167-25MG	25 mg	$395.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C18H17BrN2O2S/c19-12-6-4-11(5-7-12)18-15-3-1-2-14(15)16-10-13(24(20,22)23)8-9-17(16)21-18/h1-2,4-10,14-15,18,21H,3H2,(H2,20,22,23)
InChI key	YNCXHXYZTLIZTO-UHFFFAOYSA-N
Quality Level	100
SMILES string	BrC1=CC=C(C2C(CC=C3)C3C(C=C(S(N)(=O)=O)C=C4)=C4N2)C=C1
solubility	DMSO: 20 mg/mL, clear
storage temp.	−20°C

Biochem/physiol Actions:	4BP-TQS is an atypical agonist of a7-nAChR that binds to the receptor in an intrasubunit cavity, and activates the channel via a mechanism that is distinct from conventional agonists. Maximal activation of a7-nAChR by 4BP-TQS is eight fold greater than activation by a maximum dose of acetylcholine (Ach), and 4BP-TQS can poteniate an EC₁₀ concentration of ACh to invoke a response that is 540-fold higher than the maximal dose of ACh alone.
Biochem/physiol Actions:	4BP-TQS is an atypical agonist of a7-nAChR.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

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