IMM-01
SIGMA/SML1064 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 218795-74-5
Empirical Formula (Hill Notation): C12H17N3O2S
Molecular Weight: 267.35
Linear Formula: C12H17N3O2S
Product Type: Chemical
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML1064-5MG.
This image depicts SML1064-5MG.
| assay | ≥98% (HPLC) |
| color | white to light brown |
| form | powder |
| InChI | 1S/C12H17N3O2S/c1-12(2,3) |
| InChI key | LTFUAYRGVLQXKC-NTUHNPAUSA |
| Quality Level | 100  |
| SMILES string | S=C(NN=Cc1c(cc(cc1)O)O) |
| solubility | DMSO: 10 mg/mL, clear |
| storage temp. | 2-8°C |
| Application: | IMM-01 has been used as a formin activator to study its effects on motor neurons (MNs). |
| Biochem/physiol Actions: | IMM-01 binds and activates formin thereby leading to autoinhinition. |
| Biochem/physiol Actions: | IMM-01 is an agonist of the mammalian Diaphanous (mDia)-related formins that triggers actin assembly and microtubule stabilization, serum response factor-mediated gene expression, cell-cycle arrest, and apoptosis. IMM-01 inhibits DID–DAD binding, which in turn activates mDia family of formins in cells. IMM-01 slows tumor growth in a mouse xenograft model of colon cancer. |
| Biochem/physiol Actions: | IMM-01 is an agonist of the mammalian Diaphanous (mDia)-related formins that triggers actin assembly. |
| Packaging: | 5, 25 mg in glass bottle |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |