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2-D08

SIGMA/SML1052 - ≥98% (HPLC)

Synonym: 2′,3′,4′-trihydroxy-flavone; 2-(2,3,4-Trihydroxyphenyl)-4H-1-Benzopyran-4-one

CAS Number: 144707-18-6
Empirical Formula (Hill Notation): C15H10O5
Molecular Weight: 270.24
Linear Formula: C15H10O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1052-5MG 5 mg
 $129.00
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C15H10O5/c16-10-6-5-9(14(18)15(10)19)13-7-11(17)8-3-1-2-4-12(8)20-13/h1-7,16,18-19H
InChI key JJAXTFSPCLZPIW-UHFFFAOYSA-N
Quality Level 100 
SMILES string [o]1c2c([c](cc1c3c(c(c(cc3)O)O)O)=O)cccc2
solubility DMSO: 20 mg/mL, clear
storage temp. 2-8°C
Application: 2-D08 has been used as a small ubiquitin-like modifier (SUMO)ylation inhibitor.
Biochem/physiol Actions: 2-D08 is a potent and cell-permeable inhibitor of sumoylation that block the transfer of SUMO (small ubiquitin-like modifier) from the E2 enzyme (Ubc9) thioester conjugate to the substrate.
Biochem/physiol Actions: 2-D08 is a potent and cell-permeable inhibitor of sumoylation.
Packaging: 5 mg in glass bottle
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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