A-278637
SIGMA/SML1033 - ≥98%
Synonym: (9S)
CAS Number: 227609-66-7
Empirical Formula (Hill Notation): C17H15BrFNO3S
Molecular Weight: 412.27
Linear Formula: C17H15BrFNO3S
Product Type: Chemical
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This image depicts SML1033-25MG.
This image depicts SML1033-25MG.
| assay | ≥98% |
| color | white to beige |
| form | powder |
| optical activity | [α]/D -44 to -54°, c = 0.1 in acetonitrile |
| Quality Level | 100  |
| solubility | DMSO: 5 mg/mL, clear (warmed) |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | A-278637 is a selective opener of ATP-sensitive K (KATP) channels (EC50 = 102 nM) that blocks contraction of bladder smooth muscle in both in vivo and in vitro assays. A-278637 is 15-fold more selective than nifedipine for bladder compared other smooth muscle KATP channels, and displays reduced effects on mean arterial pressure compared to other channel openers. |
| Biochem/physiol Actions: | A-278637 is a selective opener of ATP-sensitive K (KATP) channels. |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |