Synonym: (R)-3-[2,6-cis-Di(4-methoxyphenethyl)piperidin-1-yl]propane-1,2-diol hydrochloride; 3-[(2R,6S)-2,6-Bis[2-(4-methoxyphenyl)ethyl]-1-piperidinyl]-(2R)-1,2-propanediol hydrochloride
CAS Number: 1356447-90-9
Empirical Formula (Hill Notation): C26H37NO4 · HCl
Molecular Weight: 464.04
Linear Formula: C26H37NO4 · HCl
Product Type: Chemical
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This image depicts SML0851-25MG.
| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/C26H37NO4.ClH/c1-30-25-14-8-20(9-15-25)6-12-22-4-3-5-23(27(22)18-24(29)19-28)13-7-21-10-16-26(31-2)17-11-21;/h8-11,14-17,22-24,28-29H,3-7,12-13,18-19H2,1-2H3;1H/t22-,23+,24-;/m1./s1 |
| InChI key |
FLFFCQKGCYZDOI-SJUVJREQSA-N |
| Quality Level |
100  |
| SMILES string |
Cl.N1([C@H](CCC[C@H]1CCc3ccc(cc3)OC)CCc2ccc(cc2)OC)C[C@@H](O)CO |
| solubility |
H2O: 3 mg/mL, clear |
| storage temp. |
2-8°C |
| Biochem/physiol Actions: |
GZ-793A is a selective inhibitor of vesicular monoamine transporter 2 (VMAT2), which transports the monoamine neurotransmitters from cellular cytosol into synaptic vesicles. GZ-793A is 50-fold selective for VMAT over the serotonin or dopamine transporters. VMAT2 has recently been considered a target for the treatment of methamphetamine abuse. In rat studies, GZ-793A decreased self-administration of methamphetamine with no development of tolerance. |
| Biochem/physiol Actions: |
GZ-793A is a selective inhibitor of vesicular monoamine transporter 2 (VMAT2). |
| Packaging: |
5, 25 mg in glass bottle |
| Symbol |
GHS09 |
| Signal word |
Warning |
| Hazard statements |
H410 |
| Precautionary statements |
P273 - P501 |
| Hazard Codes |
N |
| Risk Statements |
50/53 |
| Safety Statements |
60-61 |
| RIDADR |
UN 3077 9 / PGIII |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |