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WZB-117

SIGMA/SML0621 - ≥98% (HPLC)

Synonym: 3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate); 3-Hydroxy-benzoic acid 1,1′-(3-fluoro-1,2-phenylene) ester

CAS Number: 1223397-11-2
Empirical Formula (Hill Notation): C20H13FO6
Molecular Weight: 368.31
MDL Number: MFCD24387113
Linear Formula: C20H13FO6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0621-5MG 5 mg
 $136.00
1/EA		 Add To Favorites
45-SML0621-25MG 25 mg
 $574.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML0621-5MG.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C20H13FO6/c21-16-8-3-9-17(26-19(24)12-4-1-6-14(22)10-12)18(16)27-20(25)13-5-2-7-15(23)11-13/h1-11,22-23H
InChI key FRSWCCBXIHFKKY-UHFFFAOYSA-N
Quality Level 100 
SMILES string O=C(C1=CC=CC(O)=C1)OC2=C(F)C=CC=C2OC(C3=CC(O)=CC=C3)=O
solubility DMSO: 20 mg/mL, clear
storage condition desiccated
storage temp. 2-8°C
Application: WZB-117 has been used to study its tumor initiating ability in cancer stem cells. It has also been used to study the effect of glucose antagonists on 2-NBDG (2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose) uptake.
Biochem/physiol Actions: WBZ 117 is an inhibitor of basal glucose transport in H1299 lung and other cancer cells.
Biochem/physiol Actions: WBZ 117 is an inhibitor of basal glucose transport.
Biochem/physiol Actions: WZB-117 is an irreversible inhibitor. In cancer cells, WZB-117 prevents cell growth by stimulating apoptosis in any glucose concentration. It targets self-renewal and tumor-initiating capacity in cancer stem cells.
Packaging: 5, 25 mg in glass bottle
Hazard Codes N
Risk Statements 50
Safety Statements 61
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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