Lixivaptan
SIGMA/SML0603 - ≥96% (HPLC)
Synonym: N-
CAS Number: 168079-32-1
Empirical Formula (Hill Notation): C27H21ClFN3O2
Molecular Weight: 473.93
Linear Formula: C27H21ClFN3O2
Product Type: Chemical
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML0603-25MG.
This image depicts SML0603-25MG.
| assay | ≥96% (HPLC) |
| color | white to beige |
| description | 4% w/w in ethyl acetate |
| form | powder |
| InChI | 1S/C27H21ClFN3O2/c1-17-8- |
| InChI key | PPHTXRNHTVLQED-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | Fc1cc(c(cc1)C)C(=O)Nc2cc( |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | room temp |
| Biochem/physiol Actions: | Arginine vasopressin (AVP) plays an important part in circulatory and water homoeostasis and is important in renal hemodynamic alterations, water retention, and cardiac remodeling in congestive heart failure (CHF). Lixivaptan is an AVP V2-receptor selective antagonist that increases water excretion and normalizes serum sodium levels. Lixivaptan has been in clinical trials for hyponatremia associated with heart failure. |
| Biochem/physiol Actions: | Lixivaptan is an arginine vasopressin (AVP) V2-receptor antagonist. |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥96% (HPLC) |
| Storage Temp. | room temp |
| UNSPSC | 51111800 |