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CP-94,253 dihydrochloride

SIGMA/SML0588 - ≥98% (HPLC)

Synonym: 1,4-Dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one dihydrochloride; 3- (1,2,5,6-Tetrahydro-4-pyridyl)-5-propoxypyrrolo[3, 2-b] pyridine hydrochloride; 5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine hydrochloride; CP-94253 hydrochloride

CAS Number: 131084-35-0 (free base)
Empirical Formula (Hill Notation): C15H19N3O · 2HCl
Molecular Weight: 330.25
Linear Formula: C15H19N3O · 2HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0588-25MG 25 mg
 $452.00
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This image depicts SML0588-25MG.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C15H19N3O.2ClH/c1-2-9-19-14-4-3-13-15(18-14)12(10-17-13)11-5-7-16-8-6-11;;/h3-5,10,16-17H,2,6-9H2,1H3;2*1H
InChI key HGFPLQPNCZQRLO-UHFFFAOYSA-N
Quality Level 100 
SMILES string Cl.Cl.CCCOc1ccc2[nH]cc(C3=CCNCC3)c2n1
solubility H2O: 15 mg/mL, clear
storage condition desiccated
storage temp. room temp
Biochem/physiol Actions: CP-94,253 is a potent and selective serotonin 5-HT1B receptor agonist with approximately 25x and 40x selectivity over the closely related 5-HT1D and 5-HT1A receptors. Ki values are 89, 2, 860, 49 and 1,600 nM for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D and 5-HT2 receptors respectively. CP-94,253 was found to be anxiolytic in animal models; dose-dependently enhanced reinforcing effects of cocaine (self-administration);and reduced food intake.
Biochem/physiol Actions: CP-94,253 is a potent and selective serotonin 5-HT1B receptor agonist.
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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