Hydroxy-Dynasore

SIGMA/SML0340 - ≥98% (HPLC)

Synonym: 3-Hydroxy-2-naphthalenecarboxylic acid 2-[(2,4,5-trihydroxyphenyl)methylene]hydrazide; 3-Hydroxy-N′-[(2,4,5-trihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide

CAS Number: 1256493-34-1
Empirical Formula (Hill Notation): C₁₈H₁₄N₂O₅
Molecular Weight: 338.31
MDL Number: MFCD23704787
Linear Formula: C₁₈H₁₄N₂O₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML0340-5MG	5 mg	$141.00 1/EA	Add To Favorites
45-SML0340-25MG	25 mg	$557.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	faintly yellow to dark yellow
form	powder
InChI	1S/C18H14N2O5/c21-14-8-17(24)16(23)7-12(14)9-19-20-18(25)13-5-10-3-1-2-4-11(10)6-15(13)22/h1-9,21-24H,(H,20,25)/b19-9+
InChI key	UAXHPUSKEWEOAP-DJKKODMXSA-N
Quality Level	100
SMILES string	Oc1cc(O)c(C=NNC(=O)c2cc3ccccc3cc2O)cc1O
solubility	DMSO: >10 mg/mL
storage condition	protect from light
storage temp.	2-8°C

Biochem/physiol Actions:	Hydroxy-Dynasore is a cell permeable and potent dynamin inhibitor that prevents uptake of recombinant botulinum neurotoxin A heavy chain binding domain (BoNT/A-Hc). Apparently, Hydroxy-Dynasore prevents dynamin-mediated fission of endocytic vesicles from the plasma membrane.
Biochem/physiol Actions:	Hydroxy-Dynasore is a cell permeable and potent dynamin inhibitor.
Other Notes:	Air sensitive.
Packaging:	5, 25 mg in glass bottle

Hazard Codes	N
Risk Statements	50
Safety Statements	61
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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