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Telbivudine

SIGMA/SML0293 - ≥98% (HPLC)

Synonym: β-L-Thymidine; 1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-Pyrimidinedione; 2′-Deoxy-L-thymidine; Epavudine; L-Thymidine; NV 02B; Sebivo

CAS Number: 3424-98-4
Empirical Formula (Hill Notation): C10H14N2O5
Molecular Weight: 242.23
MDL Number: MFCD02683612
Linear Formula: C10H14N2O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0293-5MG 5 mg
 $144.00
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45-SML0293-25MG 25 mg
 $577.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML0293-25MG.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1
InChI key IQFYYKKMVGJFEH-CSMHCCOUSA-N
optical activity [α]/D -15 to -22°, c = 1 in H2O
Quality Level 100 
SMILES string CC1=CN([C@@H]2C[C@@H](O)[C@H](CO)O2)C(=O)NC1=O
solubility H2O: 10 mg/mL (clear solution)
storage temp. 2-8°C
Application: Telbivudine has been used to explore the mechanisms of telbivudine (LdT) induced creatine kinase (CK) elevation.
Biochem/physiol Actions: Telbivudine is a nucleoside analog that is widely used to treat hepatitis B virus (HBV) infection.
Biochem/physiol Actions: Telbivudine is a synthetic molecule containing β-L-configuration. Telbivudine improves the estimated glomerular filtration rate (eGFR) in response to chronic hepatitis B (CHB). It prevents perinatal transmission and enhances the hepatitis B e antigen (HBeAg) seroconversion. It is also known to cause side effects such as creatine kinase (CK) elevation and fatal rhabdomyolysis.
Biochem/physiol Actions: Telbivudineis a Hepatitis B antiviral agent.
Packaging: 5, 25 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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