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LG100268

SIGMA/SML0279 - ≥98% (HPLC)

Synonym: 2-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)cyclopropyl]pyridine-5-carboxylic acid; AGN 192620; ALRT 268.; CD 3127; LG268; LGD 100268; LGD 1268

CAS Number: 153559-76-3
Empirical Formula (Hill Notation): C24H29NO2
Molecular Weight: 363.49
MDL Number: MFCD01758574
Linear Formula: C24H29NO2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0279-25MG 25 mg
 $626.00
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C24H29NO2/c1-15-12-18-19(23(4,5)9-8-22(18,2)3)13-17(15)24(10-11-24)20-7-6-16(14-25-20)21(26)27/h6-7,12-14H,8-11H2,1-5H3,(H,26,27)
InChI key SLXTWXQUEZSSTJ-UHFFFAOYSA-N
Quality Level 100 
SMILES string Cc1cc2c(cc1C3(CC3)c4ccc(cn4)C(O)=O)C(C)(C)CCC2(C)C
solubility DMSO: ≥5 mg/mL (warmed)
storage temp. −20°C
Biochem/physiol Actions: LG100268 (LG268) is a potent and selective rexinoid and retinoid-X receptor (RXR) agonist. LG100268 binds to the α, β and γ RXR receptors with an IC50 = 3-4 nM and has no activity at the RAR retinoic acid receptors.
Biochem/physiol Actions: LG100268 is a retinoid-X receptor (RXR) agonist.
Features and Benefits: This compound is featured on the Nuclear Receptors (Non-Steroids)  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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