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Candesartan cilexetil

SIGMA/SML0245 - ≥98% (HPLC)

Synonym: 2-ethoxy-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-Benzimidazole-7-carboxylic acid 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester; TCV 116; TCY 116

CAS Number: 145040-37-5
Empirical Formula (Hill Notation): C33H34N6O6
Molecular Weight: 610.66
MDL Number: MFCD00871371
Linear Formula: C33H34N6O6
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML0245-10MG 10 mg
$93.00
1/EA
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45-SML0245-50MG 50 mg
$380.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: SML0245-50MG

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C33H34N6O6/c1-3-42-32-34-28-15-9-14-27(31(40)43-21(2)44-33(41)45-24-10-5-4-6-11-24)29(28)39(32)20-22-16-18-23(19-17-22)25-12-7-8-13-26(25)30-35-37-38-36-30/h7-9,12-19,21,24H,3-6,10-11,20H2,1-2H3,(H,35,36,37,38)
InChI key GHOSNRCGJFBJIB-UHFFFAOYSA-N
originator Takeda
Quality Level 100 
SMILES string CCOc1nc2cccc(C(=O)OC(C)OC(=O)OC3CCCCC3)c2n1Cc4ccc(cc4)-c5ccccc5-c6nnn[nH]6
solubility DMSO: ≥15 mg/mL
storage temp. 2-8°C
Biochem/physiol Actions: Candesartan cilexetil is a non-peptide angiotensin (AT2) receptor antagonist.
Biochem/physiol Actions: Candesartan cilexetil is the prodrug form of the potent angiotensin II receptor antagonist, candesartan. The prodrug is cleaved by esterases within the intestine to liberate the active molecule.
Features and Benefits: This compound is featured on the Angiotensin Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by Takeda . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 10 mg in glass bottle
Packaging: 50 mg in poly bottle
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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