Anti-phospho-Casein Kinase II α (pTyr255) antibody produced in rabbit
SIGMA/SAB4504299 - affinity isolated antibody
Product Type: Chemical
Immunohistochemistry Anti-phoshpho-Casein Kinase II α (pTyr255): Cat. No. SAB4504299: Immunohistochemistry analysis of paraffin-embedded Human ovary carcinoma.
Western Blotting Anti-phoshpho-Casein Kinase II α (pTyr255): Cat. No. SAB4504299: Western blot analysis of extracts from HeLa cells and Jurkat cells.
ELISA Anti-phoshpho-Casein Kinase II α (pTyr255): Cat. No. SAB4504299: ELISA for Immunogen Phosphope(pTide (left) and Non-Phosphope(pTide (right).
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | ~1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 45 kDa |
| NCBI accession no. | P68400   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pTyr255) |
| technique(s) | ELISA: 1:10000 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P68400 |
| Biochem/physiol Actions: | Casein kinase II α(CK2) regulates T-cell polarization by initiating the activation of dendritic cells. CK2 participates in the development of breast carcinoma. Mutations in CK2 results in neurodevelopmental abnormalities and dysmorphic features. This protein induces prosurvival and proinflammatory signaling pathways. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Casein kinase II α(CK2) is a pleiotropic serine/threonine kinase, that is located on human chromosome 16p13. 2-p13. 3. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Casein Kinase II alpha around the phosphorylation site of Tyr255. Immunogen Range: 221-270 |
| Physical form: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |