Anti-DGAT1 antibody produced in rabbit

SIGMA/SAB4301075 - affinity isolated antibody

Synonym: ARAT; ARGP1; DGAT

Product Type: Product-on-demand

Catalog Number	PKG Qty.	Price


45-SAB4301075-100UL	100 µL	$357.00 1/EA	Add To Favorites

Immunohistochemistry Anti-DGAT1: Cat. No. SAB4301075: Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using Anti-DGAT1 antibody.

Immunoblotting Anti-DGAT1: Cat. No. SAB4301075: Western blot analysis of extracts from Mouse heart tissue using Anti-DGAT1 antibody.

Properties
Descriptions
Safety Info.
Basic Data

accession no.	NP_036211.2
antibody form	affinity isolated antibody
antibody product type	primary antibodies
biological source	rabbit
clone	polyclonal
concentration	2.8 mg/mL
conjugate	unconjugated
form	buffered aqueous solution
isotype	IgG
mol wt	55 kDa
Quality Level	100
shipped in	wet ice
species reactivity	rat, mouse, human
storage temp.	−20°C
target post-translational modification	unmodified
technique(s)	immunohistochemistry: 1:50- 1:200
	western blot: 1:500-1:2000 (Cell Lysate)
UniProt accession no.	O75907

Application:	Anti-DGAT1 antibody produced in rabbit has been used in immunoblotting.
Biochem/physiol Actions:	Diacylglycerol-acyltransferase 1 (DGAT1) converts diacylglycerol and fatty acyl-CoA to triacylglycerol. It participates in energy storage. DGAT1 plays a key role in cancer progression. Activity of DGAT1 is essential for the physiologic absorption of vitamin D. Absence of DGAT1 activity is linked with body weight and adiposity reduction, and increased insulin sensitivity. Aberrations in the DGAT1 gene are associated with congenital diarrheal disorder (CDD).
Biochem/physiol Actions:	The antibody detects endogenous levels of total DGAT1 protein.
Disclaimer:	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits:	Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description:	Diacylglycerol-acyltransferase 1 (DGAT1), a transmembrane protein, is a member of the membrane-bound O-acyltransferase superfamily. It is seen in the endoplasmic reticulum of several cells. DGAT1 is ubiquitously expressed in humans. A high level of mRNA is seen in the small intestine. It has three transmembrane domains. The DGAT1 gene is mapped to human chromosome 8q24.3.
Immunogen:	Synthetic peptide corresponding to a region derived from internal residues of human diacylglycerol O-acyltransferase 1
Physical form:	Rabbit IgG in pH7.3 PBS, 0.05% NaN₃, 50% Glycerol.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	−20°C
UNSPSC	12352203

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