Anti-MET (Ab-1003) antibody produced in rabbit
SIGMA/SAB4300599 - affinity isolated antibody
Synonym: Anti-AUTS9 antibody produced in rabbit; Anti-HGFR antibody produced in rabbit; Anti-RCCP2 antibody produced in rabbit; Anti-c-Met antibody produced in rabbit; Anti-met proto-oncogene (hepatocyte growth factor receptor) antibody produced in rabbit
MDL Number: MFCD01633070
Product Type: Chemical
Immunohistochemistry Anti-MET (Ab-1003): SAB4300599: Analysis of paraffin-embedded human breast carcinoma tissue using Anti-MET (Ab-1003) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunoblotting Anti-MET (Ab-1003): SAB4300599: Analysis of extracts from A431 and HepG2 cells using Anti-MET (Ab-1003) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| immunogen sequence | (V-D-Y-R-A) |
| isotype | IgG |
| mol wt | ~156 kDa |
| NCBI accession no. | NP_000236.2   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | rat, human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
| western blot: 1:500-1:1000 | |
| UniProt accession no. | P08581 |
| Biochem/physiol Actions: | MET/c-Met (mesenchymal-epithelial transition factor) controls several biological processes like cell scattering, survival, proliferation, migration and c-MET signaling.(31) |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | MET/c-Met (mesenchymal-epithelial transition factor) is a tyrosine kinase receptor , that is located on chromosome 7q31. |
| General description: | Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival. |
| Immunogen: | Peptide sequence around aa. 1001-1005 (V-D-Y-R-A), according to the protein MET. |
| Physical form: | Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |