Anti-NKX2-1 antibody produced in rabbit
SIGMA/SAB3500757 - affinity isolated antibody
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of NKX2-1 in human lung tissue with NKX2-1 antibody at 2.5 μg/mL.
Immunofluorescence Immunofluorescence of NKX2-1 in human lung tissue with NKX2-1 antibody at 20 μg/mL.
Immunoblotting Anti-NKX2-1; Cat. No. SAB3500757; Western blot analysis of NKX2-1 in Rat lung tissue lysate with NKX2-1 antibody at (A) 1 and (B) 2 μ/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| mol wt | 41 kDa |
| NCBI accession no. | P43699   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, rat, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | ELISA: suitable |
| western blot: suitable | |
| UniProt accession no. | P43699 |
| Biochem/physiol Actions: | NK2 homeobox 1(NKX2-1) has a role in the development of thyroid glands, lungs and brain. It modulates gene expression during embryogenesis. NKX2-1 has been found to be expressed in adenocarcinoma and small cell lung cancer. This protein acts as an immunohistological marker to distinguish between primary lung carcinoma and non-pulmonary cancer. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | NK2 homeobox 1 (NKX2-1) is expressed in epithelial cells of the thyroid gland and lungs. The gene encoding NKX2-1 is localized on human chromosome 14q13. |
| Immunogen: | Antibody was raised against a 16 amino acid peptide near the amino terminus of human NKX2-1. |
| Other Notes: | The action of this antibody can be blocked using blocking peptide SBP3500757 . |
| Physical form: | Supplied at 1 mg/mL in PBS with 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |