Anti-CBX2
SIGMA/SAB2108627 - affinity isolated antibody
Synonym: Anti- M33; Anti- MGC10561; Anti- SRXY5; Anti-CDCA6
Product Type: Product-on-demand
Immunoblotting Cell Type: fetal heart (Cat. No. SAB2108627). Lanes 1. Antibody dilution (concentration) 0.5 μg/mL in cell type fetal heart
Western Blotting Western Blot of CBX2 in Human Fetal Heart with CBX2 antibody at 1 μg/mL
Western Blotting Western Blot of CBX2 in Human Fetal Liver with CBX2 antibody at 1 μg/mL
Western Blotting Western Blot of CBX2 in Human Adult Placenta with CBX2 antibody at 1 μg/mL
| accession no. | NM_005189 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5-1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 56 kDa |
| shipped in | wet ice |
| species reactivity | dog, guinea pig, rat, human, rabbit, bovine, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| UniProt accession no. | Q14781   |
| Biochem/physiol Actions: | CBX2 Contains 1 A.T hook DNA-binding domain and 1 chromo domain. CBX2 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ′Lys-119′, rendering chromatin heritably changed in its expressibility. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human CBX2 |
| Other Notes: | Synthetic peptide located within the following region: SSSSSSSTSSSSSSDEEDDSDLDAK |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |