Anti-GADD45B
SIGMA/SAB2108614 - affinity isolated antibody
Synonym: Anti- MYD118
Product Type: Product-on-demand
Immunohistochemistry Immunohistochemistry of GADD45B in Human Prostate Cancer with GADD45B antibody at 4-8 μg/mL
Immunoblotting Cell Type: HepG2 (Cat. No. SAB2108614). Lanes 1. Antibody dilution (concentration) 0.25 μg/mL in cell type HepG2
Immunoblotting GADD45B Antibody: Cat. No. SAB2108614: Western Blot analysis of GADD45B in Human HepG2 cell lysates with GADD45B Antibody at 1.0 μg/mL.
Western Blotting Western Blot of GA45B in Human Fetal Lung with GA45B antibody at 1 μg/mL
Western Blotting Western Blot of GADD45B in Human Lung Tumor with GADD45B antibody at 1 μg/mL
Western Blotting Western Blot of GADD45B in Human Jurkat Whole Cell with GADD45B antibody at 1 μg/mL
Western Blotting Western Blot of GADD45B in Mouse Small Intestine with GADD45B antibody at 1 μg/mL
| accession no. | NM_015675 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5-1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 18 kDa |
| shipped in | wet ice |
| species reactivity | bovine, human, dog, horse, pig, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunoblotting: suitable |
| immunohistochemistry: suitable | |
| UniProt accession no. | O75293   |
| Biochem/physiol Actions: | sGrowth arrest and DNA damage-inducible 45 (GADD45B) acts as a tumor suppressor gene through p53-mediated apoptotic pathways. GADD45B helps to maintain chondrocyte homeostasis by regulating the expression of collagen gene. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Growth arrest and DNA damage-inducible 45 (GADD45B) gene is located on human chromosome 19p13.3. |
| Immunogen: | Synthetic peptide directed towards the middle region of human GADD45B |
| Other Notes: | Synthetic peptide located within the following region: FCCDNDINIVRVSGMQRLAQLLGEP |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |