Anti-DNM1L, (N-terminal) antibody produced in rabbit
SIGMA/SAB2105834 - affinity isolated antibody
Synonym: Anti-DLP1; Anti-DRP1; Anti-DVLP; Anti-DYMPLE; Anti-HDYNIV
Product Type: Chemical
Immunohistochemistry Immunohistochemistry of DNM1L in Mouse Brain with DNM1L antibody at 4-8 μg/mL
Immunoblotting Anti-DNM1L (N-Terminal): Cat. No. SAB2105834: DNM1L in Hela cell lysates with DNM1L antibody at 1.0 μg/mL.
Western Blotting Western Blot of DNM1L in Mouse Brain with DNM1L antibody at 1 μg/mL
Western Blotting Western Blot of DNM1L in Human MCF7 Whole Cell with DNM1L antibody at 1 μg/mL
Western Blotting Western Blot of DNM1L in Human DLD1 Whole Cell with DNM1L antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 82 kDa |
| NCBI accession no. | NM_012062   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, rat, guinea pig, horse, dog, rabbit, bovine, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | O00429 |
| Biochem/physiol Actions: | The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human DNM1L |
| Other Notes: | Synthetic peptide located within the following region: IRQEIENETERISGNNKGVSPEPIH |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |