Anti-ATXN3, (N-terminal) antibody produced in rabbit
SIGMA/SAB2105749 - affinity isolated antibody
Synonym: Anti-AT3; Anti-ATX3; Anti-JOS; Anti-MJD; Anti-MJD1
Product Type: Chemical
Immunoblotting Anti-ATXN3 (N-Terminal): Cat. No. SAB2105749: ATXN3 in 293T cell lysates with ATXN3 antibody at 1.0 μg/mL.
Western Blotting Western Blot of ATXN3 in Human with ATXN3 antibody at 1 μg/mL
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 41 kDa |
| NCBI accession no. | NM_004993   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, bovine, mouse, guinea pig, sheep, horse, dog, rat |
| storage temp. | −20°C |
| technique(s) | western blot: suitable |
| UniProt accession no. | P54252 |
| Biochem/physiol Actions: | Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the N terminal region of human ATXN3 |
| Other Notes: | Synthetic peptide located within the following region: SIAHQLDEEERMRMAEGGVTSEDYR |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |