Anti-WNT10B antibody produced in rabbit
SIGMA/SAB2103278 - affinity isolated antibody
Synonym: Anti-WNT-12
Product Type: Chemical
Immunohistochemistry Anti-WNT10B: Cat. No. SAB2103278: Immunohistochemistry of WNT10B in Heart tissue with WNT10B antibody at 4-8 μg/mL.
Immunoblotting Anti-WNT10B, antibody produced in rabbit: Cat. No. SAB2103278: Immunoblotting analysis of WNT10B in Jurkat cell lysate with WNT10B anitbody at 1 μg/mL.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| concentration | 0.5 mg - 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 40 kDa |
| NCBI accession no. | NM_003394   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, dog, bovine, horse, human, guinea pig, rat, rabbit |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| western blot: suitable | |
| UniProt accession no. | O00744 |
| Biochem/physiol Actions: | WNT10B is the ligand for members of the frizzled family of seven transmembrane receptors. WNT10B is a probable developmental protein. It may be a signaling molecule which affects the development of discrete regions of tissues. WNT10B is likely to signal over only few cell diameters.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | Synthetic peptide directed towards the middle region of human WNT10B |
| Other Notes: | Synthetic peptide located within the following region: GTSGSCQFKTCWRAAPEFRAVGAAL |
| Physical form: | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |