ANTI-PAX8 antibody produced in mouse
SIGMA/SAB1412449 - clone 1A6, purified immunoglobulin, buffered aqueous solution
Synonym: PAX8
Product Type: Chemical
Immunofluorescence Immunofluorescence of monoclonal antibody to PAX8 on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting Western Blot analysis of PAX8 expression in transfected 293T cell line by PAX8 monoclonal antibody, clone 1A6. Lanes Lane 1: PAX8 transfected lysate (48.119 kDa). Lane 2: Non-transfected lysate.
ELISA Detection limit for recombinant GST tagged PAX8 is approximately 3 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 1A6, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG2aκ |
| mol wt | antigen 75.24 kDa |
| NCBI accession no. | BC001060   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| indirect immunofluorescence: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q06710 |
| General description: | This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternateively spliced transcript variants encoding different isoforms have been described. (provided by RefSeq) |
| Immunogen: | PAX8 (AAH01060, 1 a.a. ~ 450 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MPHNSIRSGHGGLNQLGGAFVNGRP |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |