ANTI-ZNF207 antibody produced in mouse
SIGMA/SAB1412396 - clone 8G7, purified immunoglobulin, buffered aqueous solution
Synonym: BuGZ; hBuGZ; DKFZp761N202; ZNF207
Product Type: Chemical
Immunofluorescence Immunofluorescence of monoclonal antibody to ZNF207 on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting ZNF207 monoclonal antibody, clone 8G7 Western Blot analysis of ZNF207 expression in HeLa S3 NE.
Western Blotting Western Blot analysis of ZNF207 expression in transfected 293T cell line by ZNF207 monoclonal antibody, clone 8G7. Lanes Lane 1: ZNF207 transfected lysate (49.7 kDa). Lane 2: Non-transfected lysate.
Western Blotting QC Western Blot detection against Immunogen (37.84 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 8G7, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG2aκ |
| mol wt | antigen 37.84 kDa |
| NCBI accession no. | NM_003457   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| indirect immunofluorescence: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | O43670 |
| Biochem/physiol Actions: | Zinc finger protein 207 (ZNF207) maintains BUB3 (budding uninhibited by benzimidazoles 3) protein stability and chromosome congression. This protein interacts with microtubules and maintains chromosome alignment. It also helps in the loading of Bub3 protein to the kinetochores. ZNF207 is essential for maintaining the viability of glioblastoma stem cells. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Zinc finger protein 207 (ZNF207) consists of a N-terminal zinc finger domain and a conserved GLE-2-binding sequence (GLEBS) motif, which helps BUB3 (budding uninhibited by benzimidazoles 3) binding. The gene is located on human chromosome 17q11.2. |
| Immunogen: | ZNF207 (NP_003448, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MGRKKKKQLKPWCWYCNRDFDDEKI |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |