Anti-COIL antibody produced in rabbit
SIGMA/SAB1411471 - purified immunoglobulin, buffered aqueous solution
Synonym: CLN80; p80-coilin
Product Type: Chemical
Western Blotting Western Blot analysis of COIL expression in transfected 293T cell line by COIL polyclonal antibody. Lanes Lane 1: COIL transfected lysate (62.60 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | antigen 62.6 kDa |
| NCBI accession no. | NM_004645   |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P38432 |
| General description: | The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. (provided by RefSeq) |
| Immunogen: | COIL (NP_004636.1, 1 a.a. ~ 576 a.a) full-length human protein. Sequence MAASETVRLRLQFDYPPPATPHCTA |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |