Monoclonal Anti-EXOSC8, (C-terminal) antibody produced in mouse
SIGMA/SAB1404932 - clone 4B3, purified immunoglobulin, buffered aqueous solution
Synonym: CIP3; EAP2; OIP2; RP11-421P11.3; RRP43; Rrp43p; bA421P11.3; p9
Product Type: Chemical
Immunofluorescence Immunofluorescence of monoclonal antibody to EXOSC8 on HeLa cell. [antibody concentration 15 μg/mL]
Western Blotting QC Western Blot detection against Immunogen (36.74 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 4B3, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG2aκ |
| mol wt | antigen ~37.11 kDa |
| NCBI accession no. | NM_181503   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| indirect ELISA: suitable | |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | Q96B26 |
| General description: | This gene encodes a 3′-5′ exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6. (provided by RefSeq) |
| Immunogen: | EXOSC8 (NP_852480.1, 177 a.a. ~ 276 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence AEVNLKKKSYLNIRTHPVATSFAVF |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |