Monoclonal Anti-JAG1 antibody produced in mouse
SIGMA/SAB1403531 - clone 1B7, purified immunoglobulin, buffered aqueous solution
Synonym: AGS; AHD; AWS; CD339; HJ1; JAGL1; MGC104644
Product Type: Chemical
Immunoblotting Monoclonal Anti-JAG1: Cat. No. SAB1403531: Antibody concentration: 1 μg/mL. Specific band of ~38.1 kDa using immunogen protein lysate.
Western Blotting QC Western Blot detection against Immunogen (38.1 kDa).
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 1B7, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG2bκ |
| mol wt | antigen ~38.1 kDa |
| NCBI accession no. | NM_000214   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| western blot: 1-5 μg/mL | |
| UniProt accession no. | P78504 |
| General description: | The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. (provided by RefSeq) |
| Immunogen: | JAG1 (NP_000205, 905 a.a. ~ 1014 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence HKGHSECPSGQSCIPILDDQCFVHP |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |