Monoclonal Anti-NLRP2 antibody produced in mouse
SIGMA/SAB1403297 - clone 1B10, purified immunoglobulin, buffered aqueous solution
Synonym: CLR19.9; FLJ20510; NALP2; NBS1; PAN1; PYPAF2
Product Type: Chemical
ELISA Detection limit for recombinant GST tagged NLRP2 is 3 ng/mL as a capture antibody.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | 1B10, monoclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| isotype | IgG2aκ |
| mol wt | antigen ~119.17 kDa |
| NCBI accession no. | BC039269   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: suitable |
| UniProt accession no. | Q9NX02 |
| General description: | NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM |
| Immunogen: | NLRP2 (AAH39269, 1 a.a. ~ 846 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MVSSAQMGFNLQALLEQLSQDELSK |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |