Anti-TNK2 antibody produced in rabbit
SIGMA/SAB1401511 - purified immunoglobulin, buffered aqueous solution
Synonym: ACK; ACK1; FLJ44758; FLJ45547; p21cdc42Hs
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to TNK2 on HeLa cell. [antibody concentration 20 μg/mL]
Western Blotting TNK2 rabbit polyclonal antibody. Western Blot analysis of TNK2 expression in IMR-32.
Western Blotting Western Blot analysis of TNK2 expression in transfected 293T cell line by TNK2 polyclonal antibody. Lanes Lane 1: TNK2 transfected lysate (39.80 kDa). Lane 2: Non-transfected lysate.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | BC008884.2   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | Q07912 |
| General description: | This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. (provided by RefSeq) |
| Immunogen: | TNK2 (AAH08884.1, 1 a.a. ~ 352 a.a) full-length human protein. Sequence MQPEEGTGWLLELLSEVQLQQYFLR |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |