Anti-RAD23B antibody produced in mouse
SIGMA/SAB1400235 - IgG fraction of antiserum, buffered aqueous solution
Synonym: Anti-HHR23B; Anti-HR23B; Anti-P58
MDL Number: MFCD02263041
Product Type: Chemical
Immunofluorescence Immunofluorescence of antibody to RAD23B on HeLa cell. [antibody concentration 10 μg/mL]
Western Blotting RAD23B polyclonal antibody. Western Blot analysis of RAD23B expression in rat brain.
Western Blotting Western Blot analysis of RAD23B expression in transfected 293T cell line by RAD23B polyclonal antibody. Lanes Lane 1: RAD23B transfected lysate (44.99 kDa). Lane 2: Non-transfected lysate.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect immunofluorescence: suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | P54727   |
| General description: | The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. (provided by RefSeq) |
| Immunogen: | RAD23B (AAH20973.1, 1 a.a. ~ 409 a.a) full-length human protein. Sequence MQVTLKTLQQQTFKIDIDPEETVKA |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |