Anti-MNDA antibody produced in mouse
SIGMA/SAB1400168 - IgG fraction of antiserum, buffered aqueous solution
Synonym: Anti-PYHIN3
MDL Number: MFCD01322329
Product Type: Chemical
Immunohistochemistry Immunoperoxidase of antibody to MNDA on formalin-fixed paraffin-embedded human lymph node. [antibody concentration 3 μg/mL]
Western Blotting Western Blot analysis of MNDA expression in transfected 293T cell line by MNDA polyclonal antibody. Lanes Lane 1: MNDA transfected lysate (44.77 kDa). Lane 2: Non-transfected lysate.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable |
| western blot: 1 μg/mL | |
| UniProt accession no. | P41218   |
| General description: | The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. (provided by RefSeq) |
| Immunogen: | MNDA (NP_002423.1, 1 a.a. ~ 407 a.a) full-length human protein. Sequence MVNEYKKILLLKGFELMDDYHFTSI |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |