ANTI-SNAIL (N-TERM D24) antibody produced in rabbit
SIGMA/SAB1306281 - IgG fraction of antiserum, buffered aqueous solution
Synonym: Protein snail homolog 1; SNAH; SNAI1; Zinc finger protein SNAI1
Product Type: Chemical
Immunoblotting Anti-SNAIL (N-term D24): Cat. No. SAB1306281: Western blot analysis of SNAIL (arrow) using Rabbit polyclonal hSNAIL-D24 . 293 cell lysates (2 μg). Lanes: 1. Nontransfected with the SNAIL gene 2. Transiently transfected with the SNAIL gene
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| application(s) | research pathology |
| biological source | rabbit |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 29083 Da |
| NCBI accession no. | NP_005976.2   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: 1:10-1:50 |
| western blot: 1:1000 | |
| UniProt accession no. | O95863 |
| Application: | ANTI-SNAIL (N-TERM D24) antibody produced in rabbit has been used in Western Blotting. |
| Biochem/physiol Actions: | Snail family transcriptional repressor 1 (SNAIL) acts as a repressor of genes associated with the epithelial phenotype like E-cadherin and increases the expression of genes linked with the mesenchymal phenotype. It has a role in epithelial-mesenchymal transition. The protein aids in G1 transition (early to late) in the cell cycle. SNAIL also modulates cell-matrix adhesion. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Snail family transcriptional repressor 1 (SNAIL) is a transcription factor and the gene encoding it is localized on human chromosome 20q13.13. |
| Physical form: | Supplied in PBS with 0.09% (W/V) sodium azide |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |